Study of CD117 abundance on ovarian cancer EVs
We are pleased to inform you that our article "Expression level of CD117 (KIT) on ovarian cancer extracellular vesicles correlates with tumor aggressiveness" is published in Frontiers in Cell and Developmental Biology
In this work, we analyzed the correlation between CD117 expression and the histological type of ovarian tumor.
We have demonstrated that expression of CD117 on tumor cells and its abundance on EVs isolated from cell cultures and body fluids of ovarian cancer patients correlate with tumor type, grade and therapy resistance status. Moreover, using EVs isolated from ovarian cancer ascites, we have shown that recurrent disease is characterized by a much higher abundance of CD117 on EVs than the primary tumor. The results of our pilot study demonstrate that CD117 profiling on EVs could be potentially used in liquid biopsy tests for characterization of aggressivity of ovarian tumors.
We are the winners of call #1 of the Women TechEU program!
We are very proud to be a winner of the Women TechEU program! Exosome Analytics will not only receive a grant, but also customized services that will help us accelerate early-stage clinical studies of our ovarian cancer diagnostic tool!